Fairweather July 31, 2010 Share Fairweather Member July 31, 2010 http://www.youtube.com/watch?v=38if0pyeli8&feature=player_embedded#! this is a pretty good video even though its pretty old but its still got a lot of good info, i've always been anti aspartame and people always tell me i'm being anal about healthy eating.. 100% of industry related studies claiming aspartame to be safe, and 100% of independent studies flagging some sort of health concern raises some eyebrows but commercial advertising is more powerful than a handful of independent studies. Brain Damage in Infant Mice Following Oral Intake of Glutamate, Aspartate, or Cysteine; Nature 1970;227-609-610 Funded By: Washington University Conclusion/Findings: Irreversible degenerative changes and acute neuronal necrosis http://www.nature.com/nature/journal/v227/n5258/pdf/227609b0.pdf Year Published: 2008 Full Reference: Direct and Indirect Cellular Effects of Aspartame on the Brain. European Journal of Clinical Nutrition (2008) 62, 451-462; P. Humphries, E. Pretorius, and H. Naude Conclusion/Findings: Excessive aspartame ingestion might cause certain mental disorders, as well as compromised learning and emotional functioning Hyperlink to Study: http://www.newmediaexplorer.org/sepp/aspartamebrain.pdf Year Published: 2007 Full Reference: Life-Span Exposure to Low Doses of Aspartame Beginning During Prenatal Life Increases Cancer Effects in Rats, Morando Soffritti, Fiorella Belpoggi, Eva Tibaldi, Davide Degli Esposti, Michelina Lauriola; Environmental Health Perspectives, 115(9) Sep 2007; 115:1293-1297. doi:10.1289/ehp.10271. Conclusion/Findings: Carcinogenicity proven a second time; with effects increased when exposure to aspartame begins during fetal life. Hyperlink to Study:http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info:doi/10.1289/ehp.10271 Year Published: 1984 Full Reference: Effects of Aspartame and Glucose on Rat Brain Amino Acids and Serotonin. Yokogoshi H, Roberst CH, Caballero B, Wurtman RJ. American Journal of clinical Nutrition. 1984 July, 40(1):1-7 Funded By: MIT Conclusion/Findings: High aspartame doses can generate major neurochemical changes in rats, especially when consumed along with carbohydrate-containing foods Year Published: 1984 Full Reference: Revelance of Animal Studies to Human Safety. Olney, JW. Neurobehavioral Toxicology and Teratology. 1984; 6:455-462 Funded By: MIT Conclusion/Findings: Excitotoxins, as used in foods today, may produce blood elevations high enough to cause damage to the nervous system of young children, damage which is not detectable at the time of occurrence but which may give rise to subtle disturbances in neuroendocrine function in adolescence and/or adulthood. Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/6152304 Year Published: 1996 Full Reference: Increasing Brain Tumor Rates: Is There a Link to Aspartame? Olney JW, Farber NB, Spitznagel E, Robins LN. Journal of Neuropatholgy & Experimental Neurology. 1996 Nov; 55(11):1115-23 Funded By: NIH Conclusion/Findings: Brain tumor incidence in the US implicates the introduction of aspartame into the American diet. Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/8939194 Year Published: 2000 Full Reference: Glutamate and Aspartate Impair Memory Retention and Damage Hypothalamic Neurons in Adult Mice. Cheol Hyoung Park, Se Hoon Coi, et al. Toxicology Letters, Vol. 115, Issue 2, May 19, 2000, pp. 117-125 Funded By: Not known Conclusion/Findings: Found that aspartate shortens the memory response, impairs memory retention and damages hypothalamic neurons in mice Hyperlink to Study: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCR-408BJC1-4&_user=10&_coverDate=05%2F19%2F2000&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1411118226&_rerunOrigin=scholar. google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=3ebc362ec75c9f1f41642537e52a8667 Year Published: 2002 Full Reference: Effect of Aspartame on N-Methyl-D Asparate Sensitive L-(311) Glutamate Binding Sites in Rat Brain Synpatic Membranes, AV Glushakov, DM Dennis, et al. Molecular Psychiatry, 2002, Vol. 7, No. 4, pp. 359-367. Funded By: University of Florida Conclusion/Findings: Shows that aspartate has a role in causing mental retardation, but the mechanism by which it does that is still unknown. Hyperlink to Study: http://www.nature.com/mp/journal/v7/n4/full/4000976a.html Year Published: 2006 Full Reference: The Effect of Aspartame Metabolites on Human Erythrocyte Membrane Acetylcholinesterase Activity. Stylianos Tsakiris, Aglaia Giannoulia-Karantana, et al., Pharmacological Research, Volv. 53, Issue 1, Jan. 2006. pp. 1-5. Conclusion/Findings: Found that high concentrations of aspartame can cause neurological symptoms, including memory and learning problems. Hyperlink to Study: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WP9-4H0BSYT-1&_user=10&_coverDate=01%2F31%2F2006&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1411153110&_rerunOrigin=scholar. google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=cec27b55d31f63ae899cb1ec33ea4dd7 Year Published: 2008 Full Reference: Direct and Indirect Cellular Effects of Aspartame on the Brain, P Humphries, E Pretorius and H Naude, European Journal of Clinical Nutrition , 2008, 62, 451-462 Conclusion/Findings: Asserts that excessive aspartame ingestion might be involved in the pathogenesis of certain mental disorders (DSM-IV-TR 2000) and also in compromised learning and emotional functioning. Hyperlink to Study: http://www.nature.com/ejcn/journal/v62/n4/abs/1602866a.html Year Published: 1986 Full Reference: Evaluation of Reactions to Food Additives: The Aspartame Experience. MK Bradstock, MK Serdula, JS Marks, RJ Barnard, Nt Crane, PL Remington and FL Trowbridge. The American Journal of Clinical Nutrition. Vol. 43, pp. 464-469, 1986 Conclusion/Findings: Identified some case reports in which the symptoms may be attributable to aspartame in commonly-consumed amounts. Headache, mood alterations (anxiety, agitation, irritability, or depression), insomnia, dizziness, and fatigue were the most frequently reported symptoms, with one case of a child in a double-blind test who became hyperactive after consuming products with aspartame. Hyperlink to Study: http://www.ajcn.org/cgi/content/abstract/43/3/464 Year Published: 1993 Full Reference: Adverse Reactions to Aspartame: Double-Blind Challenge in Patients from a Vulnerable Population. Ralph G. Walton, Robert Hudak, Ruth J. Green-Waite. Psychiatry. July 1, 1993. Vol. 34, Issue 1, pp. 13-17. Funded By: Dept. of Psychiatry Northeastern Ohio,Universities College of Medicine and University Hospital of Cleveland Conclusion/Findings: Found that individuals with mood disorders are particularly sensitive to this artificial sweetener and its use in this population should be discouraged. In the clinical study, the project was halted by the Institutional Review Board after a total of 13 individuals had completed the study because of the severity of reactions within the group of patients with a history of depression Hyperlink to Study: http://www.biologicalpsychiatryjournal.com/article/0006-3223%2893%2990251-8/abstract Year Published: 1991 Full Reference: Effect of Aspartame and Protein, Administered in Phenylalanine-Equivalent Doses, on Plasma Neutral Amino Acids, Aspartate, Insulin and Glucose in Man, Svend E. Moller; Pharmacology & Toxicology, Vol. 68, Issue 5, pp. 408-412. Funded By: Clinical Research Laboratory, Denmark Conclusion/Findings: The study showed that the intake of aspartame in a not unrealistically high dose produced a marked and persistent increase of the availability of Phe to the brain, which was not observed after protein intake. The study indicated, furthermore, that Phe was cleared faster from the plasma after consumption of protein compared with aspartame. Hyperlink to Study: http://www3.interscience.wiley.com/journal/122214234/abstract Year Published: 1987 Full Reference: Aspartame Effects on Brain Serotonin, RI Wurtman, Letter in American Journal of Clinical Nutrition, 1987 April; 45(4):799-803 Funded By: MIT Conclusion/Findings: Argues that using rodents to disprove aspartame’s harm to humans is not relevant, and that it reacts more negatively in humans than in mice Hyperlink to Study: http://www.ajcn.org/cgi/reprint/45/4/799.pdf ...this isn't even half of them Quote Link to comment Share on other sites More sharing options...
VooDooPC July 31, 2010 Share VooDooPC Member July 31, 2010 This is how they make stuff "Diet", right? Quote Link to comment Share on other sites More sharing options...
Fairweather July 31, 2010 Author Share Fairweather Member July 31, 2010 This is how they make stuff "Diet", right? yes sir Quote Link to comment Share on other sites More sharing options...
samurai nightling July 31, 2010 Share samurai nightling Member July 31, 2010 You name a food that is produced and packaged by some big company, and I will show you an ingredient that is known to be unhealthy for you. Am i still going to eat it? Yes. And it'll taste good too. And I'll still live to be prolly 70 or more. Quote Link to comment Share on other sites More sharing options...
VooDooPC July 31, 2010 Share VooDooPC Member July 31, 2010 Who doesn't love azodicarbonamide!? I can't get enough. Quote Link to comment Share on other sites More sharing options...
Tristan August 13, 2010 Share Tristan Member August 13, 2010 Donald Rumsfeld got aspartame passed by the FDA because he was the CEO of G. D. Searle who manufactured an artificial sweetener that uses aspartame. Quote Link to comment Share on other sites More sharing options...
JackieChan August 14, 2010 Share JackieChan GC Alumni August 14, 2010 Sorry to be off topic, but whenever I see the topic title I keep thinking it's saying "apartofme", or something to do with "sparta". Quote Link to comment Share on other sites More sharing options...
ValenAlvern August 14, 2010 Share ValenAlvern Member August 14, 2010 Who drinks diet? Quote Link to comment Share on other sites More sharing options...
lousiest August 14, 2010 Share lousiest Member August 14, 2010 I used to, thinking it was healthier than regular, till I saw a documentary on it. Scary stuff Quote Link to comment Share on other sites More sharing options...
mohawk August 15, 2010 Share mohawk Member August 15, 2010 I used to, thinking it was healthier than regular, till I saw a documentary on it. Scary stuff linky please Quote Link to comment Share on other sites More sharing options...
lousiest August 15, 2010 Share lousiest Member August 15, 2010 I used to, thinking it was healthier than regular, till I saw a documentary on it. Scary stuff linky please was on tv, nat geo i believe Quote Link to comment Share on other sites More sharing options...
ValenAlvern August 15, 2010 Share ValenAlvern Member August 15, 2010 (edited) I used to, thinking it was healthier than regular, till I saw a documentary on it. Scary stuff I laughed at my mother when she said thats why she drinks diet. I was... 13 at the time, Im 22 now. Edited August 15, 2010 by ValenAlvern Quote Link to comment Share on other sites More sharing options...
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