After a few waves of nausea, I got the hang of it. You just don't look directly at the side monitors and keep them in your per... side vision and you're all set. I found it very useful. And that's my setup at my office. I already had a 3x1 + 1 setup for my job. Just added a new active DP adapter to get the Eyefinity going.
And thanks Merc, I'm sure you could smoke like crazy in Dark Carnival with this setup.
Overall:
+1 Would play again.