AND...
C - backwards
D - use (or E), depends
Mouse 3 - aim, or in multiplayer games, it's the mic, so R becomes aim
V - crouch
...
I've played this way forevers. Asking me not to is like telling a right-handed person to write with their left.
I also have to invert my mouse.
This usually isn't such a problem in games. Mass Effect 3, though - it used Right Mouse to scan planets, and since I rebind that key to Forward, the game decided it didn't like that, and I couldn't scan planets which you really need to do to advance the plot. The only fix was to edit some game system file, manually reassigning the scan Right Mouse to something else. GAH!!! Dumb programming!